Week 6 discussion 2 physiology and pathophysiology
The pathophysiology of CKD involves a gradual loss of nephrons within the kidneys resulting in decreased ability to filter toxins as well as excrete waste products and excess water. Clinical manifestations depend on stage but may include edema, fatigue, nausea, anemia, confusion and poor appetite.
Evaluation consists of objective testing such as urinalysis and imaging studies while treatment focuses on slowing progression through lifestyle modifications like following a low sodium diet or engaging in regular physical activity. Medications can also be used to manage symptoms such as high blood pressure or anemia while dialysis may be necessary for more severe cases when kidney function has declined too much for other methods to effectively help.
Overall, although CKD cannot be cured it is still important to monitor closely with regular visits as early detection can make all the difference when it comes to managing its long-term effects.