Advanced medical coding: diagnostic testing
The diagnosis codes assigned to Rietti-Greppi-Micheli anemia (RGM) are D58.1 and D70.2.
D58.1 is the ICD-10 code for hereditary spherocytosis, which is a type of hemolytic anemia caused by defective red blood cell membrane proteins and can be seen in RGM cases.
D70.2 is the ICD-10 code for Microangiopathic Hemolytic Anemia (MAHA), which is defined as a condition caused by microvascular damage to red blood cells leading to their premature destruction and hemoglobinuria, and can also be seen in cases of RGM anemia due to accompanying thrombotic occlusion of small vessels in the bone marrow or elsewhere.
In order to properly diagnose RGM anemia, physicians typically complete a comprehensive physical exam with detailed family history as well as diagnostic testing including CBC count, reticulocyte count, direct antiglobulin test (DAT), peripheral blood smear, osmotic fragility testing, Hb electrophoresis or DNA analysis for mutation identification if necessary; these tests are used to confirm the presence of abnormal circulating red cells that cause hemolysis in patients with RGM anemia. Treatment plans may involve iron supplementation therapy, folic acid supplementation therapy or even splenectomy depending on the severity of symptoms and degree of organ involvement present in each individual case.