Identify examples of concepts and issues and discuss how these are involved or addressed.

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Concepts:
1. Hormone Replacement Therapy (HRT): A medical strategy used to treat symptoms of menopause by introducing hormones, such as estrogen and progesterone, into the body in order to restore hormonal balance.
2. Menopause: The transition experienced by women when their menstrual cycle ends and they stop producing ova. It is associated with a variety of physical and psychological changes due to the cessation of hormone production.
3. Risk-Benefit Analysis: An evaluation process that weighs both potential risks and benefits associated with any medical treatment or therapy in order to make an informed decision about whether it should be pursued or not.

Issues:
1. Side Effects: Potential side effects are an important factor when considering any form of hormone replacement therapy because some treatments may cause adverse reactions or worsen existing conditions if not monitored closely or managed appropriately.
2. Cancer Risks: Women who take certain types of HRT have been found to have an increased risk for certain cancers, such as breast cancer, so this must be taken into account before beginning treatment and monitored throughout its course if it is chosen as a viable option for symptom relief during menopause transition periods.
3. Informed Decision Making: All patients considering hormone replacement therapy must be well informed about both possible risks and benefits in order to make an educated choice that suits their individual needs best while minimizing chances of harm from side effects or cancer risks associated with these treatments.